This second article on Looking ahead to Grant Cycle 7 – Strategy examines the Strategy’s “Mutually reinforcing contributory and evolving objectives” from the viewpoint of: Community, Rights and Gender; resilient and sustainable systems for health; pandemic preparedness and the COVID-19 Response Mechanism; and Health Financing. It explores the nuances of Grant Cycle 7 and its future implications, the call for collective efforts and the challenges ahead.
As our first article in this series noted, the Board paper on Strategy Implementation: Acceleration into Grant Cycle 7, discussed at November Board meeting, looks at how elements of the Global Fund’s Strategy 2023-2028 have been addressed through funding requests (FRs) submitted in the first three Windows of Grant Cycle 7 (GC7). In that article we covered the three diseases; in this we look at Communities, Equity, Human Rights and Gender (CEHRG); resilient and sustainable systems for health (RSSH); pandemic preparedness (PP) and the COVID-19 Response Mechanism (C19RM). The third article in the series will look at Health Financing and NextGen Market Shaping.
Unfortunately, well-resourced and coordinated global anti-rights and anti-gender movements are making significant progress in eroding the rights of LGBTQ communities, women and girls, and other key and vulnerable populations (KVPs). In all regions, key populations (KPs) and organizations that work with them are facing increasingly hostile political rhetoric, crackdowns on their activities, and restrictions on civic space that are putting them and their work at risk.
However, programs to address HRG-related barriers, increase equity and strengthen the leadership and engagement of communities build a strong foundation that enables communities and their organizations to adapt when risks increase or crises occur. These evidence-based programs reinforce the impact of Global Fund grants and improve disease outcomes.
as Figure 2 shows:

This was evident in more than 80% of FRs, including interventions aimed at promoting equity and community wellbeing. Nevertheless, expanding high-quality programs continues to be a hurdle.
In GC7 FR , requests to address human rights-related barriers plateaued at 66% of grants compared to GC6. Requests addressing gender-related barriers increased from 58% in GC6 to 70% in GC7. An average of 82% of FRs included equity-oriented outcomes. Countries that received Matching Funds and technical support through the Breaking Down Barriers Initiative had higher quality interventions to address HRG- related barriers. An average of 81% included well-defined roles for community-led and -based organizations in service delivery. Integrating quality programs at scale, across the portfolio remains a challenge, particularly in the face of increasing attacks on HRG equality; an increased focus on intersectional approaches is needed.

The Global Fund is adopting a more ambitious and systematic approach in GC7, characterized by key partnerships, requirements such as the Gender Equality Marker, and new definitions and guidance to support the assessment of HRG equality risks in country, program and grant contexts, to identify appropriate mitigation strategies. It is implementing the community, rights and gender (CRG)- related Strategic Initiatives (SIs), including supporting safety and security assessments of KP implementers. Providing technical assistance (TA) to strengthen community engagement and leadership will also mitigate some of the risks in highly volatile contexts. Training on HRG and CSS risks has been held within the Secretariat.
As part of its commitment to the Strategy, the Global Fund will:
up programs and initiatives and expand coverage in more countries to improve the safety and security of KP programs, strengthen community-led monitoring (CLM), and address HRG-related barriers
and implement new ideas and initiatives to reach populations left behind, such as work to reach last-mile TB KPs, and get funding to women, girls and gender-diverse communities through the Gender Equality Fund.
new approaches to increasing equity-oriented programming and intersectional approaches.
capacity across the partnership to respond consistently, clearly, and effectively to crises, in a way that does no harm to communities.
to strengthen Secretariat's approach to equity and intersectionality.
The Global Fund plays a crucial role in global health systems and pandemic preparedness and response (PPR), being the largest multilateral grant financier. Its focus on key systems functions complements collaborative efforts with prominent organizations such as Gavi, the Global Financing Facility (GFF), the Pandemic Fund and the World Bank, aiming for comprehensive health system reforms and effective PP.


The COVID-19 context in GC6 made RSSH investment implementation somewhat challenging as grants were delayed, ministries had other urgent priorities and TA could not be effectively deployed. However, there are underlying structural factors propelling low RSSH implementation that should be tackled for GC7.


78% of the C19RM reinvestments and PO Wave 2 Awards (as of 6 October) reflect the shift to RSSH and PPR, with strong, fit-for-purpose country consultation demonstrated.
Good examples of innovative, effective country governance and implementation arrangements, e.g., Zambia Ministry of Health (MOH) Principal Recipient (PR) delegated lead convening authority and implementation oversight responsibilities to the Zambia National Public Health Institute (NPHI)
including custom Workplan Tracking Measures to guide programming.
✓ The Global Fund is not a recipient of PF funds from its first call for proposals; efforts are underway to ensure complementarity of investments (the PF first call focused on three of the same investment areas as PO Wave 2).
✓ Leveraging Country Coordinating Mechanisms (CCMs) and MOHs (as PR for many C19RM grants and PF proposal leads) to strengthen alignment between investments at country level and enhance community and civil society engagement.
✓ The Global Fund is actively engaging with the PF to strengthen collaboration going forward; awaiting lessons learned and next steps from the PF.
The Fund welcomes suggestions for strengthening RSSH-PPR implementation for GC7 and C19RM, and on how to best position the Global Fund going into the Eighth Replenishment.
Looking ahead to GC7 implementation, stakeholders highlighted the significance of SIs and Matching Funds in advancing CRG and CLM. Concerns about reduced investments and the impact of lower funding on CRG were raised by some of the stakeholders who also called for increased multi-country funding to address stigma and discrimination, especially in cross-border initiatives benefiting displaced persons.
People emphasized the need for a holistic approach, strong leadership at the country level, and coordination among partners to achieve set objectives, cautioning against assuming the inherent readiness of CCMs. They proposed accelerating efforts to get HTM achievements back on track while documenting cross-cutting benefits with factors like RSSH, PPR, reducing health inequities, and climate change.
Stakeholders emphasized the importance of reviewing country commitments to UN meetings on TB, Universal Health Coverage (UHC), and pandemic preparedness. They acknowledged progress in returning to essential health services after COVID-19 but expressed concerns about emerging challenges such as wars, climate change, and threats to human rights. Some acknowledged that the shift towards RSSH/PPR is crucial and recommended mid-term reviews.
Many commended efforts to address COVID-19 challenges and were worried about funding gaps post-Seventh Replenishment. They raised questions about the discontinuing funding for regional Green Light Committees and called attention to underperforming KPIs. They continued to advocate for ongoing investment in harm reduction, pre-exposure prophylaxis (PrEP) uptake, and equitable access. Finally, they stressed the importance of community and civil society participation, disaggregated data, and a review of the Global Fund Sustainability, Transition and Co-financing Policy in 2024.
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